Famed archaeologist/adventurer Dr. Henry "Indiana" Jones is called back into action when he becomes entangled in a Soviet plot to uncover the secret behind mysterious artifacts known as the Crystal Skulls.
The newest Indiana Jones adventure begins in the desert Southwest in 1957 – the height of the Cold War. Indy and his sidekick Mac have barely escaped a close scrape with nefarious Soviet agents on a remote airfield. Now, Professor Jones has returned home to Marshall College – only to find things have gone from bad to worse. His close friend and dean of the college explains that Indy's recent activities have made him the object of suspicion and that the government has put pressure on the university to fire him. On his way out of town, Indiana meets rebellious young Mutt, who carries both a grudge and a proposition for the adventurous archaeologist: If he'll help Mutt on a mission with deeply personal stakes, Indy could very well make one of the most spectacular archaeological finds in history – the Crystal Skull of Akator, a legendary object of fascination, superstition and fear. But as Indy and Mutt set out for the most remote corners of Peru, they quickly realize the Soviet agents are also hot on the trail of the Crystal Skull. Indy and Mutt must find a way to evade the ruthless Soviets, follow an impenetrable trail of mystery, grapple with enemies and friends of questionable motives, and, above all, stop the powerful Crystal Skull from falling into the deadliest of hands.